Systemic mastocytosis
Systemic mastocytosis is a rare disease in which, due to a mutation, the body has an excessive amount of mast cells Mast cells normally participate in defense against disease and wound healing If you have systemic mastocytosis, mast cells accumulate in different parts of the body
Once activated, mast cells release certain substances, which can cause you to experience symptoms such as facial flushing, itching, fast heart rate, abdominal cramps, feeling like your heart is racing or missing your heart. Common triggers include alcohol, temperature changes, spicy foods, and certain medications
Systemic mastocytosis is divided into 7 subtypes All common forms develop slowly, while some others develop rapidly Mast cell leukemia and mast cell sarcoma are the rarest forms of systemic mastocytosis