Cholera
Cholera is a bacterial disease that spreads mostly through contaminated water Cholera causes severe diarrhea and dehydration Without treatment, cholera can even cause death within hours in previously healthy people
Due to modern water purification and filtration techniques, cholera almost no longer exists in industrialized countries. The last significant case was recorded in 1911 in the USA Cholera still exists in Africa, Southeast Asia, Haiti, and central Mexico The risk of cholera outbreaks is high when poverty, war or natural disasters force people to live in large groups without adequate sanitation.
Cholera treatment is quite simple and cheap Because the bacteria causes dehydration, the treatment is fluid transfusions This can prevent fatal complications
The bacterium Vibrio cholerae causes cholera infection The effects of the disease are caused by a strong toxin – cholera toxin, which the bacterium releases in the small intestine. Cholera toxin sticks to the intestinal wall, where it prevents the normal flow of sodium and chlorine. This causes the body to secrete large volumes of fluid, which is manifested by diarrhea and loss of fluid and electrolytes.
Contaminated water is the main source of cholera, although raw seafood, fruits or vegetables can also become a source of infection.
The cholera bacterium has two distinct life cycles One is in the environment, and the other is in people
Cholera bacterium in the environment
The cholera bacterium occurs naturally in water, where it attaches to small aquatic organisms. The cholera bacterium spreads through hosts around the world when the simplest aquatic inhabitants follow their food source, algae and plankton, which grow as water temperatures rise. Algae growth is also facilitated by uric acid, which is present in large quantities in sewage and agricultural waste.
Cholera bacteria in humans
When a person ingests cholera bacteria with water or food, he may not get sick himself, but he may excrete the bacteria in his stool. When human feces contaminate a food or water source, ideal conditions are created for the spread of cholera
Because it takes more than a million cholera bacteria (about one cup of contaminated water) to cause disease, cholera generally cannot be spread from person to person.
The most common sources of cholera infection are water and certain foods, such as seafood, raw fruits and vegetables, and grains.
standing, drinking water Cholera bacteria exist in water for a long time Drinking water is often a source of bacterial spread in populations People living in large groups without adequate sanitation are at high risk of developing cholera
Sea products Eating raw seafood, especially from certain regions, may cause infection Recent cases in the US have been linked to seafood from the Gulf of Mexico region
Raw fruits and vegetables Raw, uncooked fruits and vegetables are a common source of cholera in regions where the bacteria is endemic. In developing countries, fertilizers containing human feces or irrigation of crops with contaminated water lead to crop contamination
Cereals In areas where cholera is common, grains such as rice may become contaminated after cooking, especially if left at room temperature for several hours. This is a good environment for bacteria to grow
Most people who come into contact with the cholera bacteria (Vibrio cholerae) do not become ill and do not realize that the bacteria were in their body. However, these people shed the bacteria in their stools for up to 14 days, which could lead to the spread of the bacteria through contaminated water. Most symptomatic cases of cholera present as mild to moderate diarrhea that is difficult to distinguish from diarrhea at other times.
Only 1 in 10 people show typical signs and symptoms of cholera, usually a few days after being infected.
Symptoms of cholera may be: - Diarrhea Cholera-associated diarrhea begins soon and may cause rapid fluid loss—up to 1 liter per hour. Diarrheal mass has a mostly colorless, milky appearance, reminiscent of washed rice water.
- Nausea and vomiting Vomiting is especially common in the early stages of cholera and may last for hours
- Dehydration Dehydration may occur within hours of the onset of symptoms Depending on how much fluid a person has lost, dehydration can be mild or severe A fluid loss of more than 10% of total body weight indicates severe dehydration
- Signs and symptoms of cholera also include irritability, lethargy, "drooping" eyes, dry mouth, extreme thirst, dry skin that loses elasticity, irregular or small amounts of urine, low blood pressure, irregular heartbeat (arrhythmia)
- Dehydration may cause loss of minerals and electrolytes from the body Electrolytes regulate the distribution of fluid in the body Electrolyte imbalance develops during cholera
- Electrolyte imbalance
- Electrolyte imbalance causes severe signs and symptoms, including:
- Muscle cramps This is due to the loss of sodium, chlorine and potassium
- Shock Shock is the most dangerous complication of dehydration Shock occurs when blood pressure and oxygen concentration in the body drop due to increased blood volume Without treatment, severe hypovolemic shock can lead to death within minutes
Signs and Symptoms of Cholera in Children In general, children have the same symptoms as adults, but they are especially prone to developing low blood sugar – hypoglycemia – due to fluid loss. This can lead to:
- Changes in consciousness
- Shocks
- Coma
When to see a doctor - The risk of cholera is very small in industrialized countries Even in endemic areas, the chance of developing cholera is low if you follow safety instructions Despite this, cases of cholera are still recorded in the world If you have severe diarrhea while traveling in such regions, consult your doctor
- If you have severe diarrhea and think you may have had cholera, get help right away Severe dehydration is an emergency that requires treatment, regardless of the underlying cause